Should we care about pregabalin for elderly patients with a history of cardiac dysrhythmia?

被引：10

作者：

Laville, M. -A. ^{[1
]}

de la Gastine, B. ^{[1
]}

Husson, B. ^{[2
]}

Le Boisselier, R. ^{[1
]}

Mosquet, B. ^{[1
]}

Coquerel, A. ^{[1
]}

机构：

[1] CHR Univ Caen, Ctr Reg Pharmacovigilance Basse Normandie, F-14033 Caen, France

[2] Ctr Hosp Robert Bisson, F-14107 Lisieux, France

来源：

REVUE DE MEDECINE INTERNE | 2008年 / 29卷 / 02期

关键词：

pregabalin; sinusal tachycardia; elderly people; polypharmacy;

D O I：

10.1016/j.revmed.2007.07.009

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Pregabalin is similar in structure to gamma-aminobutyric acid. It is used for neuropathic pain, generalized anxiety disorders and as an adjunct therapy for partial seizures. Tachycardia is a rare side-effect. A 92-year-old patient with a history of paroxystic fibrillation was hospitalised for zoster. She developed a sinusal tachycardia followed by atrial fibrillation and congestive heart failure 15 It after a first dose of pregabalin. The imputation was considered as plausible. Even though the mechanism remains unclear, pregabalin might induce tachycardia in predisposed old patients. (C) 2007 Elsevier Masson SAS.

引用

页码：152 / 154

页数：3

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