The opportunity to use ion-selective membrane electrodes for dissolution tests

被引：2

作者：

Aboul-Enein, HY

Stefan, RI

机构：

[1] King Faisal Specialist Hosp & Res Ctr, Bioanalyt & Drug Dev Lab, Riyadh 11211, Saudi Arabia

[2] Univ Pretoria, Dept Chem, ZA-0002 Pretoria, South Africa

来源：

INSTRUMENTATION SCIENCE & TECHNOLOGY | 1999年 / 27卷 / 02期

关键词：

D O I：

10.1080/10739149908085836

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The dissolution test is required for tablet formulations in the view to test the place of dissolution, the time needed for this process, and the model of dissolution. The determination of the disintegration and dissolution first order constants is important. The values of these constants must be reliably assayed. In order to assay, continuously, the activity of an ion in the solution, ion-selective membrane electrodes offer better advantages to simply carry out these dissolution tests.

引用

收藏

页码：89 / 93

页数：5

相关论文

共 11 条

[1] AMITRIPTYLINE-SELECTIVE PLASTIC MEMBRANE SENSORS AND THEIR PHARMACEUTICAL APPLICATIONS [J].

BUNACIU, AA ;

IONESCU, MS ;

PALIVAN, C ;

COSOFRET, VV .

ANALYST, 1991, 116 (03) :239-243

[2] MIANSERIN ION-SELECTIVE MEMBRANE-ELECTRODE AND ITS PHARMACEUTICAL APPLICATIONS [J].

BUNACIU, AA ;

IONESCU, MS ;

STEFAN, RI ;

IOAN, I ;

ABOULENEIN, HY .

ANALYTICAL LETTERS, 1994, 27 (09) :1647-1658

[3]

Evgen'ev MI, 1998, J ANAL CHEM+, V53, P154

[4] ZERO-ORDER OR 1ST-ORDER RELEASE KINETICS OF WATER-IN-OIL-IN-WATER (W/O/W) MULTIPLE EMULSIONS OF LIPIODOL DEPENDENT ON THE TYPES OF SURFACTANTS [J].

LIN, SY ;

LUI, WY .

CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, 40 (10) :2860-2863

[5]

SAMEMOTO H, 1992, CHEM PHARM BULL, V40, P1007

[6] SYNTHESIS AND DRUG-RELEASE CHARACTERISTICS OF THE CONJUGATES OF MITOMYCIN-C WITH N-SUCCINYL-CHITOSAN AND CARBOXYMETHYL-CHITIN [J].

SONG, Y ;

ONISHI, H ;

NAGAI, T .

CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, 40 (10) :2822-2825

[7] Validation criteria for developing ion-selective membrane electrodes for analysis of pharmaceuticals [J].

Stefan, RI ;

Aboul-Enein, HY .

ACCREDITATION AND QUALITY ASSURANCE, 1998, 3 (05) :194-196

[8] Ion-selective membrane electrodes in pharmaceutical analysis [J].

Stefan, RI ;

Baiulescu, GE ;

Aboul-Enein, HY .

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 1997, 27 (04) :307-321

[9] Amiodarone-selective membrane electrode [J].

Stefan, RI ;

AboulEnein, HY ;

Baiulescu, GE .

SENSORS AND ACTUATORS B-CHEMICAL, 1996, 37 (03) :141-144

[10]

Stefan RJ, 1997, PHARMAZIE, V52, P780