Membrane lipid homeostasis in bacteria

被引：994

作者：

Zhang, Yong-Mei ^{[1
]}

Rock, Charles O. ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Infect Dis, Memphis, TN 38105 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2008年 / 6卷 / 03期

关键词：

D O I：

10.1038/nrmicro1839

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The ability of bacteria to control the biophysical properties of their membrane phospholipids allows them to thrive in a wide range of physical environments. Bacteria precisely adjust their membrane lipid composition by modifying the types of fatty acids that are produced by the biosynthetic pathway and altering the structures of pre-existing phospholipids. The recycling of phospholipids that are used as intermediates in the biosynthesis of other major membrane components is also crucial to bilayer stability in dividing cells. Here, the principal genetic and biochemical processes that are responsible for membrane lipid homeostasis in bacteria are reviewed.

引用

页码：222 / 233

页数：12

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