A simple model for DNA denaturation

Following Poland and Scheraga, we consider a simplified model for the denaturation transition of DNA. The two strands are modeled as interacting polymer chains. The attractive interactions, which mimic the pairing between the four bases, are reduced to a ingle short-range binding term. Furthermore, base-pair misalignments are forbidden, implying that this binding term exists only for corresponding (same curvilinear abscissae) monomers of the two chains. We take into account the excluded-volume repulsion between monomers of the two chains, but neglect intrachain repulsion. We nd that the excluded-volume term generates an effective repulsive interaction between the chains, which decays as 1/r(d-2). Due to this long-range repulsion between the chains, the denaturation transition is rst order in any dimension, in agreement with previous studies.