DBSubLoc: database of protein subcellular localization

被引:43
作者
Guo, T [1 ]
Hua, SJ [1 ]
Ji, XL [1 ]
Sun, ZR [1 ]
机构
[1] Tsing Hua Univ, Inst Bioinformat, Dept Biol Sci & Biotechnol, Beijing 100084, Peoples R China
关键词
D O I
10.1093/nar/gkh109
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We have built a protein subcellular localization annotation database, the DBSubLoc database, which is available at http://www.bioinfo.tsinghua. edu.cn/dbsubloc.html. Annotations were taken from primary protein databases, model organism genome projects and literature texts, and then were analyzed to dig out the subcellular localization features of the proteins. The proteins are also classified into different categories. Based on sequence alignment non-redundant subsets of the database have been built, which may provide useful information for subcellular localization prediction. The database now contains >60 000 protein sequences including similar to30 000 protein sequences in the non-redundant data sets. Online download, search and Blast tools are also available.
引用
收藏
页码:D122 / D124
页数:3
相关论文
共 17 条
[1]   Gene Ontology: tool for the unification of biology [J].
Ashburner, M ;
Ball, CA ;
Blake, JA ;
Botstein, D ;
Butler, H ;
Cherry, JM ;
Davis, AP ;
Dolinski, K ;
Dwight, SS ;
Eppig, JT ;
Harris, MA ;
Hill, DP ;
Issel-Tarver, L ;
Kasarskis, A ;
Lewis, S ;
Matese, JC ;
Richardson, JE ;
Ringwald, M ;
Rubin, GM ;
Sherlock, G .
NATURE GENETICS, 2000, 25 (01) :25-29
[2]   MGD: the Mouse Genome Database [J].
Blake, JA ;
Richardson, JE ;
Bult, RJ ;
Kadin, JA ;
Eppig, JT .
NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :193-195
[3]   The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003 [J].
Boeckmann, B ;
Bairoch, A ;
Apweiler, R ;
Blatter, MC ;
Estreicher, A ;
Gasteiger, E ;
Martin, MJ ;
Michoud, K ;
O'Donovan, C ;
Phan, I ;
Pilbout, S ;
Schneider, M .
NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :365-370
[4]   Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO) [J].
Dwight, SS ;
Harris, MA ;
Dolinski, K ;
Ball, CA ;
Binkley, G ;
Christie, KR ;
Fisk, DG ;
Issel-Tarver, L ;
Schroeder, M ;
Sherlock, G ;
Sethuraman, A ;
Weng, S ;
Botstein, D ;
Cherry, JM .
NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :69-72
[5]   Wanted: subcellular localization of proteins based on sequence [J].
Eisenhaber, F ;
Bork, P .
TRENDS IN CELL BIOLOGY, 1998, 8 (04) :169-170
[6]  
Feng ZP, 2001, BIOPOLYMERS, V58, P491, DOI 10.1002/1097-0282(20010415)58:5<491::AID-BIP1024>3.0.CO
[7]  
2-I
[8]  
FENG ZP, 2002, IN SILICO BIOL, V2, P291
[9]   PSORT-B:: improving protein subcellular localization prediction for Gram-negative bacteria [J].
Gardy, JL ;
Spencer, C ;
Wang, K ;
Ester, M ;
Tusnády, GE ;
Simon, I ;
Hua, S ;
deFays, K ;
Lambert, C ;
Nakai, K ;
Brinkman, FSL .
NUCLEIC ACIDS RESEARCH, 2003, 31 (13) :3613-3617
[10]   The FlyBase database of the Drosophila genome projects and community literature [J].
Gelbart, W ;
Bayraktaroglu, L ;
Bettencourt, B ;
Campbell, K ;
Crosby, M ;
Emmert, D ;
Hradecky, P ;
Huang, Y ;
Letovsky, S ;
Matthews, B ;
Russo, S ;
Schroeder, A ;
Smutniak, F ;
Zhou, P ;
Zytkovicz, M ;
Ashburner, M ;
Drysdale, R ;
de Grey, A ;
Foulger, R ;
Millburn, G ;
Yamada, C ;
Kaufman, T ;
Matthews, K ;
Gilbert, D ;
Grumbling, G ;
Strelets, V ;
Shemen, C ;
Rubin, G ;
Berman, B ;
Frise, E ;
Gibson, M ;
Harris, N ;
Kaminker, J ;
Lewis, S ;
Marshall, B ;
Misra, S ;
Mungall, C ;
Prochnik, S ;
Richter, J ;
Smith, C ;
Shu, S ;
Tupy, J ;
Wiel, C .
NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :172-175