Total synthesis of sanjoinine A (frangufoline)

被引：27

作者：

Xiao, D ^{[1
]}

East, SP ^{[1
]}

Joullié, MM ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 52期

基金：

美国国家科学基金会;

关键词：

alkaloids; asymmetric reactions; macrocycles; strained compounds;

D O I：

10.1016/S0040-4039(98)02278-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sanjoinine A (1) was synthesized from a 14-membered cyclopeptide prepared from a Garner aldehyde derived from D-serine. The key steps in the synthesis were the catalytic asymmetric reduction of ketone 2(b) and the final removal of the Boc group. (C) 1998 Elsevier Science Ltd. All rights reserved.

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收藏

页码：9631 / 9632

页数：2

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