A facile and efficient carbodiimide-mediated synthesis of dihydroquinazolines via a tandem nucleophilic addition-intramolecular hetero conjugate addition annulation strategy

被引：52

作者：

Saito, T

Tsuda, K

Saito, Y

机构：

[1] Department of Chemistry, Faculty of Science, Science University of Tokyo, Tokyo 162, Kagurazaka, Shinjuku-ku

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 02期

关键词：

D O I：

10.1016/0040-4039(95)02130-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient method is described for the synthesis of dihydroquinazoline derivatives which involves initial addition of a nucleophile (alcohol, amine and thiol) to the carbodiimide cumulenic system followed by intramolecular hetero conjugate addition annulation.

引用

页码：209 / 212

页数：4

共 40 条

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