Chemometric strategies for enhancing the chromatographic methodologies with second-order data analysis of compounds when peaks are overlapped

被引:60
作者
Goicoechea, H. C. [1 ]
Culzoni, M. J. [1 ]
Gil Garcia, M. D. [2 ]
Martinez Calera, M. [2 ]
机构
[1] Univ Nacl Litoral, LADAQ, Fac Bioquim & Ciencias Biol, Catedra Quim Analit 1, Santa Fe, Argentina
[2] Univ Almeria, Fac Ciencias Expt, Dept Hidrogeol & Quim Analit, La Canada De San Urbano 04120, Almeria, Spain
关键词
Chromatography; Chemometrics; Second-order data; Signal pre-treatment; MULTIVARIATE CURVE RESOLUTION; PERFORMANCE LIQUID-CHROMATOGRAPHY; IONIZATION-MASS-SPECTROMETRY; ALTERNATING LEAST-SQUARES; DIODE-ARRAY DETECTION; TRILINEAR DECOMPOSITION ALGORITHM; 8 TETRACYCLINE ANTIBIOTICS; EFFLUENT WASTE-WATER; BACKGROUND CORRECTION; CAPILLARY-ELECTROPHORESIS;
D O I
10.1016/j.talanta.2010.07.057
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This overview covers the different chemometric strategies linked to chromatographic methodologies that have been used and presented in the recent literature to cope with problems related to incomplete separation, the presence of unexpected components in the sample, matrix effect and changes in the analytical signal due to pre-treatment of sample. Among the different chemometric strategies it focuses on pre-treatment of data to correct background and time shift of chromatographic peaks and the use of second-order algorithms to cope with overlapping peaks from analytes or from analytes and interferences in liquid chromatography coupled to diode array, fast-scanning fluorescence spectroscopy and mass spectrometry detectors. Finally the review presents the strategies used to deal with changes in the analytical response as result of matrix effect in liquid and gas chromatography, as well as the use of standardization strategies to correct modifications in the analytical signal as a consequence of sample pre-treatment in liquid chromatography. (c) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:1098 / 1107
页数:10
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