Effect of precursor chemical composition on the formation and stability of G-quadruplex core supramolecular star polymers

被引：11

作者：

Gadwal, Ikhlas ^{[1
]}

De, Swati ^{[1
]}

Stuparu, Mihaiela C. ^{[2
]}

Khan, Anzar ^{[1
]}

机构：

[1] Swiss Fed Inst Technol, Dept Mat, CH-8093 Zurich, Switzerland

[2] Univ Zurich, Inst Organ Chem, CH-8057 Zurich, Switzerland

来源：

POLYMER CHEMISTRY | 2012年 / 3卷 / 09期

基金：

瑞士国家科学基金会;

关键词：

GUANOSINE DERIVATIVES; CIRCULAR-DICHROISM; ION CHANNELS; G-QUARTETS; POLYMERIZATION; DEOXYGUANOSINE; SPECTROSCOPY; ORGANIZATION; INITIATORS; CHEMISTRY;

D O I：

10.1039/c2py20371e

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

A homologous series of guanosine end-functional poly(butadiene)s has been prepared. The potassium cation-templated assembly of these guanosine functionalised precursors then furnished supramolecular star polymers with a G-quadruplex core. Comparison with the previously reported poly(ethylene glycol)-based supramolecular star polymers revealed that in designing supramolecular star polymers, chemically non-polar assembly precursors - that do not interfere with the supramolecular interactions of the core - are essential for the preparation of high stability and high molecular weight supramolecular branched architectures. In addition, in comparison to star polymers composed of chemically polar polymer chains, the non-polar supramolecular ensembles show chain-length independent properties.

引用

页码：2615 / 2618

页数：4

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