Transfer hydrogenation with Hantzsch esters and related organic hydride donors

被引：531

作者：

Zheng, Chao ^{[1
]}

You, Shu-Li ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL SOCIETY REVIEWS | 2012年 / 41卷 / 06期

关键词：

ASYMMETRIC TRANSFER HYDROGENATION; ENANTIOSELECTIVE TRANSFER HYDROGENATION; ORGANOCATALYTIC TRANSFER HYDROGENATION; CATALYZED TRANSFER HYDROGENATION; ALPHA-IMINO ESTERS; CHIRAL PHOSPHORIC-ACID; BOND-DISSOCIATION ENERGIES; TRANSITION-METAL CATALYSIS; DIRECT REDUCTIVE AMINATION; RESIN-SUPPORTED PEPTIDE;

D O I：

10.1039/c1cs15268h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In recent years, Hantzsch esters and their related organic hydride donors have been widely utilized in biomimetic approaches of asymmetric transfer hydrogenation (ATH) reactions. Various compounds containing C=C, C=N and C=O unsaturated functionalities could be reduced in the presence of organocatalysts or transition metal complexes, affording versatile chiral building blocks in high yields and excellent enantioselectivities under mild conditions. In this critical review, recent advances in this area are summarized and classified according to unsaturated functional groups being reduced and catalytic systems employed (91 references).

引用

页码：2498 / 2518

页数：21

共 185 条

[1] Organocatalytic hydride transfers: A new concept in asymmetric hydrogenations [J].