Highly chemoselective metal-free reduction of tertiary amides

被引：202

作者：

Barbe, Guillaume ^{[1
]}

Charette, Andr B. ^{[1
]}

机构：

[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 01期

关键词：

D O I：

10.1021/ja077463q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This communication describes the chemoselective metal-free reduction of tertiary amides to the corresponding amines. Hantzsch ester is used as a mild reducing agent for the reduction of trifluoromethanesulfonic anhydride activated amides providing the tertiary amines with high functional group tolerance.

引用

页码：18 / +

页数：3

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