Pediatric mastocytosis

被引：69

作者：

Hartmann, K

Metcalfe, DD

机构：

[1] NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20842 USA

[2] Univ Cologne, Dept Dermatol, D-5000 Cologne, Germany

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2000年 / 14卷 / 03期

关键词：

D O I：

10.1016/S0889-8588(05)70299-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mastocytosis is a rare disorder characterized by accumulation of mast cells in tissues. Sixty-five percent of patients with mastocytosis are children. Whereas mastocytosis in adults is usually persistent or progressive, pediatric mastocytosis is often transient and limited. Recent studies suggest that childhood-onset and adult-onset mastocytosis also differ in their pathogenesis. This article reviews the various forms of pediatric mastocytosis with a special focus on new pathogenetic findings.

引用

页码：625 / +

页数：17