A role for epithelial γδ T cells in tissue repair

My colleagues and I have a long-term interest in interactions between intraepithelial gamma delta T cells and neighboring epithelial cells. We have focused our studies on interactions in the thymus, skin, and intestine, and are investigating the development, specificity, and function of these gamma delta T cells. Our results have defined unique properties of these cells and support a specialized role for epithelial gamma delta T cells in immune surveillance, wound repair, inflammation, and protection from malignancy.