Identification of carbapenem-resistant Klebsiella pneumoniae harboring KPC enzymes in New Jersey

被引：25

作者：

Chiang, Tom ^{[2
]}

Mariano, Noriel ^{[1
,3
]}

Urban, Carl ^{[1
,3
]}

Colon-Urban, Rita ^{[4
]}

Grenner, Louise ^{[1
,3
]}

Eng, Robert H. K. ^{[2
]}

Huang, David ^{[2
]}

Dholakia, Hema ^{[2
]}

Rahal, James J. ^{[1
,3
]}

机构：

[1] New York Hosp Queens, Flushing, NY 11355 USA

[2] Vet Affairs New Jersey Hlth Care Syst, E Orange, NJ USA

[3] Weill Cornell Med Coll, New York, NY USA

[4] SUNY Coll Old Westbury, Old Westbury, NY 11568 USA

来源：

MICROBIAL DRUG RESISTANCE | 2007年 / 13卷 / 04期

关键词：

D O I：

10.1089/mdr.2007.767

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Klebsiella pneumoniae isolates harboring KPC enzymes have been identified in many geographical areas since 2001. Numerous problems exist in the detection and treatment of patients with such isolates. The clinical characteristics and molecular epidemiology associated with 12 randomly chosen patients in whom these enzymes were detected by molecular methods are described. This is the first description of the identification of carbapenem-resistant K. pneumoniae isolates harboring KPC beta-lactamases at the Veterans Administration Hospital in New Jersey (VA NJHCS). Because recognition of carbapenem resistance in K. pneumoniae due to KPC enzymes can only be achieved by molecular methods, detection in the Clinical Microbiology Laboratory by routine methods will continue to be difficult, leading to dilemmas in treatment.

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收藏

页码：235 / 239

页数：5

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