Deracemization of anti-1,2-diols leading to trans-epoxides via oxazaborolidine-mediated enantiomer-differentiating ring-cleavage of acetal derivatives

被引：17

作者：

Harada, T ^{[1
]}

Nakamura, T ^{[1
]}

Kinugasa, M ^{[1
]}

Oku, A ^{[1
]}

机构：

[1] Kyoto Inst Technol, Dept Chem, Sakyo Ku, Kyoto 6068585, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 03期

关键词：

acetals; diols; asymmetric induction; asymmetric reactions; cleavage reactions;

D O I：

10.1016/S0040-4039(98)02387-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantioconvergent transformation of racemic anti-1,2-diols to enantiomerically enriched (71-96% ee) trans-epoxides is realized via chiral oxazaborolidine-mediated enantiomer-differentiating ring-cleavage reaction of the acetal derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：503 / 506

页数：4

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