A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue

被引：73

作者：

Baek, Na Young ^{[2
,3
]}

Heo, Cheol Ho ^{[2
,3
]}

Lim, Chang Su ^{[1
]}

Masanta, Goutam ^{[2
,3
]}

Cho, Bong Rae ^{[1
]}

Kim, Hwan Myung ^{[2
,3
]}

机构：

[1] Korea Univ, Dept Chem, Seoul 136713, South Korea

[2] Ajou Univ, Div Energy Syst Res & Mol Sci, Suwon 443749, South Korea

[3] Ajou Univ, Technol Res Ctr, Suwon 443749, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 38期

关键词：

ZN2+; NEUROBIOLOGY; STIMULATION; RELEASE; BIOLOGY;

D O I：

10.1039/c2cc31077e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn2+ and can selectively detect mitochondrial Zn2+ in a rat hippocampal slice at a depth of 100-200 mu m by using two-photon microscopy.

引用

页码：4546 / 4548

页数：3

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