Electrostatic assembly of conjugated polymer thin layers on electrospun nanofibrous membranes for biosensors

被引：305

作者：

Wang, XY

Kim, YG

Drew, C

Ku, BC

Kumar, J

Samuelson, LA ^{[1
]}

机构：

[1] RDECOM Natick Soldier Ctr, Natick, MA 01760 USA

[2] Univ Massachusetts Lowell, Ctr Adv Mat, Dept Chem, Lowell, MA 01854 USA

[3] Univ Massachusetts Lowell, Ctr Adv Mat, Dept Phys, Lowell, MA 01854 USA

来源：

NANO LETTERS | 2004年 / 4卷 / 02期

关键词：

D O I：

10.1021/nl034885z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a new fabrication approach to highly sensitive optical sensors by combining the techniques of electrospinning and electrostatic layer-by-layer adsorption. A fluorescent probe, hydrolyzed poly[2-(3-thienyl) ethanol butoxy carbonyl-methyl urethane] (H-PURET), was electrostatically assembled onto the surface of cellulose acetate (CA) electrospun nanofibrous membranes. The fluorescence of these membranes can be quenched by extremely low concentrations (ppb) of methyl viologen (MV2+) and cytochrome c (cyt c) in aqueous solutions. This high sensitivity is attributed to the high surface-area-to-volume ratio of the electrospun membranes and efficient interaction between the fluorescent conjugated polymer and the analytes.

引用

页码：331 / 334

页数：4

共 17 条

[1] Highly sensitive biological and chemical sensors based on reversible fluorescence quenching in a conjugated polymer [J].