Treg Cells, Life History, and Diversity

被引：122

作者：

Benoist, Christophe ^{[1
]}

Mathis, Diane ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Div Immunol, Dept Microbiol & Immunobiol, Boston, MA 02115 USA

来源：

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY | 2012年 / 4卷 / 09期

关键词：

REGULATORY T-CELLS; INDUCE WASTING DISEASE; FOXP3; EXPRESSION; RETINOIC-ACID; IN-VIVO; AUTOIMMUNE-DISEASE; CUTTING EDGE; REG-CELLS; NEGATIVE SELECTION; RECEPTOR;

D O I：

10.1101/cshperspect.a007021

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Regulatory T cells expressing the FoxP3 transcription factor have a profound and nonredundant role in several aspects of immunological tolerance. We will review here the specification of this lineage, its population dynamics, and the diversity of subphenotypes that correlate with their diverse roles in controlling inflammation in a variety of settings.

引用

页数：14

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