The fluorescence bioassay platforms on quantum dots nanoparticles

被引:43
作者
Liu, TC [1 ]
Liu, BS
Zhang, HL
Wang, Y
机构
[1] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Wuhan 430074, Peoples R China
[2] Univ Elect Sci & Technol China, Sch Appl Math, Chengdu 610054, Peoples R China
关键词
quantum dot; nanocrystals; biolabeling; bioprobe; bioassay platform;
D O I
10.1007/s10895-005-2980-5
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In this paper, we present the optical properties and the platforms on fluorescent quantum dots for biological labeling, biomedical engineering and biosensor in molecular imaging. Quantum dots possess several properties that make them very attractive for fluorescent tagging: broad excitation spectrum, narrow emission spectrum, precise tunability of their emission peak, longer fluorescence lifetime than organic fluorophores and negligible photobleaching. We describe how to take such advantages of quantum dots to develop the technology and employ it to build assay platforms. Finally, ultrasensitivity, multicolor, and multiplexing of the technology of semiconductor quantum dots open up promising and interesting possibilities for bioassay platform.
引用
收藏
页码:729 / 733
页数:5
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