Immunopathogenesis and immunotherapy in AIDS virus infections

被引：187

作者：

Letvin, NL

Walker, BD ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Partners AIDS Res Ctr, Boston, MA 02114 USA

[2] Beth Israel Deaconess Med Ctr, Div Viral Pathogenesis, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Div AIDS, Boston, MA 02114 USA

来源：

NATURE MEDICINE | 2003年 / 9卷 / 07期

关键词：

D O I：

10.1038/nm0703-861

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The heterogeneity of HIV and the different human leukocyte antigen (HLA) backgrounds of infected individuals have posed challenges to understanding the pathogenesis of HIV infection. But continuing advances in our knowledge of the role of immune responses in controlling HIV viremia should help to define goals for immune-based therapies and vaccine strategies against AIDS.

引用

页码：861 / 866

页数：6

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