Reactive ketenes through a carbonate/amine shuttle deprotonation strategy:: Catalytic, enantioselective α-bromination of acid chlorides

被引：61

作者：

Hafez, AM ^{[1
]}

Taggi, AE ^{[1
]}

Wack, H ^{[1
]}

Esterbrook, J ^{[1
]}

Lectka, T ^{[1
]}

机构：

[1] Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 13期

关键词：

D O I：

10.1021/ol0160147

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] We have developed an efficient methodology for the generation of ketenes by employing a catalytic shuttle base and potassium carbonate as a stoichiometric base, We have applied this technology to the catalytic, asymmetric a bromination of acid chlorides.

引用

页码：2049 / 2051

页数：3

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