A pH-Triggered, Fast-Responding DNA Hydrogel

被引：492

作者：

Cheng, Enjun ^{[3
]}

Xing, Yongzheng ^{[3
]}

Chen, Ping ^{[4
]}

Yang, Yang ^{[3
]}

Sun, Yawei ^{[5
]}

Zhou, Dejian ^{[1
,2
]}

Xu, Lijin ^{[4
]}

Fan, Qinghua ^{[5
]}

Liu, Dongsheng ^{[3
]}

机构：

[1] Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England

[2] Univ Leeds, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England

[3] Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China

[4] Renmin Univ, Dept Chem, Beijing 100080, Peoples R China

[5] Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 41期

基金：

美国国家科学基金会;

关键词：

DNA; hydrogels; nanostructures; pH switches; I-MOTIF; BUILDING-BLOCKS; RICH STRAND; NANOPARTICLES; PROTEIN; CRYSTALLIZATION; NANOSTRUCTURES; TRANSITION; CRYSTALS; POLYMERS;

D O I：

10.1002/anie.200902538

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Y switch? A fast, pH-responsive DNA hydrogel (see picture; right) was prepared by a three-armed DNA nanostructure (left) assembling together through the formation of intermolecular i-motif structures (middle). The hydrogel can be switched to the non-gel state in minutes by simply using environmental pH changes. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7660 / 7663

页数：4

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