Decaspirones F-I, bioactive secondary metabolites from the saprophytic fungus Helicoma viridis

被引：48

作者：

Hu, Hejiao

Guo, Huijuan

Li, Erwei

Liu, Xingzhong

Zhou, Yuguang

Che, Yongsheng ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Microbiol, Key Lab Systemat Mycol & Lichenol, Beijing 100080, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2006年 / 69卷 / 12期

关键词：

D O I：

10.1021/np0603830

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Decaspirones F-H (1-3), three new spirobisnaphthalene derivatives, and one new non-spirobisnaphthalene, decaspirone I (4), have been isolated from cultures of an isolate of the saprophytic fungus Helicoma Viridis. The structures of these compounds were determined mainly by analysis of their NMR spectroscopic data. The absolute configuration of decaspirone F (1) was established by X-ray crystallographic analysis of its mono-bromobenzoate derivative. In standard disk assays, compounds 1- 4 showed modest activity against Pseudomonas aeruginosa (multiple antibiotic-resistant strain, ATCC 27853), and decaspirone G (2) also displayed activity against Lactococcus lacti.

引用

页码：1672 / 1675

页数：4

共 17 条

[1] STRUCTURE OF SCH-49209 - A NOVEL ANTITUMOR AGENT FROM THE FUNGUS NATTRASSIA-MANGIFERAE [J].