Positron emission tomography (PET) methodology for small animals and its application in radiopharmaceutical preclinical investigation

被引：41

作者：

Hume, SP ^{[1
]}

Jones, T ^{[1
]}

机构：

[1] Hammersmith Hosp, Royal Postgrad Med Sch, MRC, Clin Sci Ctr,PET Methodol Grp,Cyclotron Unit, London W12 0NN, England

来源：

NUCLEAR MEDICINE AND BIOLOGY | 1998年 / 25卷 / 08期

关键词：

PET; rat; radioligand; carbon-11;

D O I：

10.1016/S0969-8051(98)00055-9

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The use and usefulness of positron emission tomography (PET) to quantify the specific and selective in vivo binding of radioligands in small laboratory animals is briefly reviewed up to the end of 1996. Emphasis is placed on practical experience with a dedicated, small diameter, tomograph (built in collaboration with CTI, Knoxville, TN), implementing conventional PET methodology. NUCL MED BIOL 25;8:729-732, 1998. (C) 1998 Elsevier Science Inc.

引用

页码：729 / 732

页数：4

共 43 条

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