Blood coagulation factor VIII: An overview

被引：30

作者：

Bhopale, GM ^{[1
]}

Nanda, RK ^{[1
]}

机构：

[1] Hindustan Antibiot Ltd, Res & Dev Div, Pune 411018, Maharashtra, India

来源：

JOURNAL OF BIOSCIENCES | 2003年 / 28卷 / 06期

关键词：

blood coagulation factor VIII; hemophilia A; replacement therapy;

D O I：

10.1007/BF02708439

中图分类号：

Q [生物科学];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the clinician should be interested.

引用

页码：783 / 789

页数：7

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