Role of GTPases in Bacterial Ribosome Assembly

被引：136

作者：

Britton, Robert A. ^{[1
]}

机构：

[1] Michigan State Univ, Dept Microbiol & Mol Genet, E Lansing, MI 48824 USA

来源：

ANNUAL REVIEW OF MICROBIOLOGY | 2009年 / 63卷

基金：

美国国家科学基金会;

关键词：

translation; 50S subunit; 30S subunit; biogenesis; assembly factor; GTP-BINDING PROTEIN; GUANINE-NUCLEOTIDE-BINDING; BACILLUS-SUBTILIS GTPASE; CELL-CYCLE ARREST; ESCHERICHIA-COLI; DNA-REPLICATION; SMALL-SUBUNIT; GROWTH-RATE; RNA; ERA;

D O I：

10.1146/annurev.micro.091208.073225

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The assembly of the ribosome,a complex molecular machine composed of RNA and protein, is a poorly, understood process. Recent work his demonstrated that GTPases are likely to play key roles in the assembly of ribosomes in bacteria and eukaryotes. This review highlights several bacterial ribosome assembly GTPases (RA-GTPases) and discusses possible functions for these proteins in the biogenesis of individual ribosomal subunits and subunit joining. RA-GTPases appear to link various aspects of the cell cycle and metabolism with translation. How these RA-GTPases may coordinate these connections are discussed.

引用

页码：155 / 176

页数：22

共 108 条

[61] The gene for 16S rRNA methyltransferase (ksgA) functions as a multicopy suppressor for a cold-sensitive mutant of era, an essential RAS-Like GTP-binding protein in Escherichia coli [J].

Lu, Q ;

Inouye, M .

JOURNAL OF BACTERIOLOGY, 1998, 180 (19) :5243-5246

[62] A small protein unique to bacteria organizes rRNA tertiary structure over an extensive region of the 50 S ribosomal subunit [J].

Maeder, C ;

Draper, DE .

JOURNAL OF MOLECULAR BIOLOGY, 2005, 354 (02) :436-446

[63] The GTP-binding protein YlqF participates in the late step of 50 S ribosomal subunit assembly in Bacillus subtilis [J].

Matsuo, Y ;

Morimoto, T ;

Kuwano, M ;

Loh, PC ;

Oshima, T ;

Ogasawara, N .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (12) :8110-8117

[64] Analysis of GTPases carrying hydrophobic amino acid substitutions in lieu of the catalytic glutamine: Implications for GTP hydrolysis [J].

Mishra, R ;

Gara, SK ;

Mishra, S ;

Prakash, B .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2005, 59 (02) :332-338

[65] AtNOS/AtNOA1 Is a Functional Arabidopsis thaliana cGTPase and Not a Nitric-oxide Synthase [J].

Moreau, Magali ;

Lee, Gyu In ;

Wang, Yongzeng ;

Crane, Brian R. ;

Klessig, Daniel F. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (47) :32957-32967

[66] Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis [J].

Morimoto, T ;

Loh, PC ;

Hirai, T ;

Asai, K ;

Kobayashi, K ;

Moriya, S ;

Ogasawara, N .

MICROBIOLOGY-SGM, 2002, 148 :3539-3552

[67] The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding [J].

Muench, Stephen P. ;

Xu, Ling ;

Sedelnikova, Svetlana E. ;

Rice, David W. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (33) :12359-12364

[68]

Neidhardt FC, 1990, Physiology of the bacterial cell

[69] THE ASSEMBLY OF PROKARYOTIC RIBOSOMES [J].

NIERHAUS, KH .

BIOCHIMIE, 1991, 73 (06) :739-755

[70] Solution structure of ribosomal protein L16 from Thermus thermophilus HB8 [J].

Nishimura, M ;

Yoshida, T ;

Shirouzu, M ;

Terada, T ;

Kuramitsu, S ;

Yokoyama, S ;

Ohkubo, T ;

Kobayashi, Y .

JOURNAL OF MOLECULAR BIOLOGY, 2004, 344 (05) :1369-1383

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