The carboxyl-terminal sequence of rat intestinal mucin RMuc3 contains a putative transmembrane region and two EGF-Like motifs

被引：26

作者：

Khatri, IA

Forstner, GG

Forstner, JF

机构：

[1] HOSP SICK CHILDREN,RES INST,DIV BIOCHEM RES,TORONTO,ON M5G 1X8,CANADA

[2] UNIV TORONTO,TORONTO,ON,CANADA

[3] HOSP SICK CHILDREN,RES INST,DIV GASTROENTEROL,TORONTO,ON M5G 1X8,CANADA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1997年 / 1326卷 / 01期

基金：

英国医学研究理事会;

关键词：

mucin; intestine; EGF; carboxyl terminus; membrane domain; (rat);

D O I：

10.1016/S0005-2736(97)00063-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A 3' RACE technique was used to establish the nucleotide sequence encoding the C-terminal 379 amino acids of rat intestinal Muc3. Unlike the C-terminus of Muc2 and many secretory mucins, Muc3 contains two EGF motifs and a putative transmembrane domain. The mRNA for rat Muc3 is 7.5-8.0 kb.

引用

页码：7 / 11

页数：5