General, stereoselective synthesis of ethylene isosteres of α- and β-glycosylasparagines

被引：33

作者：

Dondoni, A ^{[1
]}

Mariotti, G ^{[1
]}

Marra, A ^{[1
]}

机构：

[1] Univ Ferrara, Dipartimento Chim, Chim Organ Lab, I-44100 Ferrara, Italy

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 18期

关键词：

amino acids; C-glycosides; glycopeptide mimetics; C-glycosylasparagines; sugar acetylenes;

D O I：

10.1016/S0040-4039(00)00403-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The coupling of alpha- or beta-D-linked lithium C-glycosyl acetylides with N-Boc D-serinal acetonide followed by the reduction of the triple bond, deoxygenation, and oxidative cleavage of the oxazolidine ring afforded alpha- and beta-anomer pairs of C-glycosyl alpha-aminopentanoic acids (gluco, manno, galacto, and 2-acetamido-galacto). (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3483 / 3487

页数：5

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