Amphiphilic peptides and their cross-disciplinary role as building blocks for nanoscience

被引:222
作者
Cavalli, Silvia [1 ,2 ]
Albericio, Fernando [1 ,2 ,3 ]
Kros, Alexander [4 ]
机构
[1] Networking Ctr Bioengn Biomat & Nanomed, CIBER BBN, Barcelona 08028, Spain
[2] Inst Res Biomed, Barcelona 08028, Spain
[3] Univ Barcelona, Dept Organ Chem, E-08028 Barcelona, Spain
[4] Leiden Univ, Inst Chem, NL-2300 RA Leiden, Netherlands
关键词
AZIDE-ALKYNE CYCLOADDITION; SIDE-CHAIN POLYMERS; SELF-COMPLEMENTARY OLIGOPEPTIDE; TRANSFER RADICAL POLYMERIZATION; SHEET LIPOPEPTIDE MONOLAYERS; ASSEMBLING ORGANIC NANOTUBES; ACID-N-CARBOXYANHYDRIDES; NATIVE CHEMICAL LIGATION; HELICAL COILED-COILS; GRAMICIDIN-S;
D O I
10.1039/b906701a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Peptides are particularly attractive as molecular building blocks in the bottom-up fabrication of supramolecular structures based on self-assembly and have potential in many important applications in the fields of biotechnology and bioengineering. In the first part of this critical review the main categories of peptide-based amphiphiles will be discussed by showing some relevant examples, which demonstrate the importance of amphiphilic peptides as molecular building blocks for nanostructures. In the second part of this review we will review the cross-disciplinary role of peptide-based supramolecular nanoarchitectures ranging from chemistry to biology, medicine, materials science, and engineering through discussing several examples of applied nanomaterials (216 references).
引用
收藏
页码:241 / 263
页数:23
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