A virus spotlighted by an autonomous DNA machine

被引：235

作者：

Weizmann, Yossi

Beissenhirtz, Moritz K.

Cheglakov, Zoya

Nowarski, Roni

Kotler, Moshe

Willner, Itamar ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Farkes Ctr Light Induced Proc, Inst Chem, IL-91904 Jerusalem, Israel

[2] Hebrew Univ Jerusalem, Hadassah Med Sch, Dept Expt Pathol, IL-91120 Jerusalem, Israel

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 44期

关键词：

biosensors; chemiluminescence; DNA structures; DNAzymes; enzymes;

D O I：

10.1002/anie.200602754

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Highly sensitive: Analysis of viral DNA (M13 phage) is possible by using a DNA-based machine that is fueled by dNTPs and synthesizes DNAzyme reporter units. The DNAzymes mimic peroxidase and lead to a colorimetric or chemiluminescent readout of the analyzed DNA. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：7384 / 7388

页数：5

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