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1 Hz repetitive transcranial magnetic stimulation of the unaffected hemisphere ameliorates contralesional visuospatial neglect in humans

被引：166
作者：
Brighina, F
Bisiach, E
Oliveri, M
Piazza, A
La Bua, V
Daniele, O
Fierro, B
机构：
[1] Univ Palermo, Neurophysiol Unit, Inst Neuropsychiat, I-90129 Palermo, Italy
[2] Univ Turin, Dept Psychol, Turin, Italy
[3] IRCCS S Lucia, Rome, Italy
[4] Univ Palermo, Dept Psychol, Palermo, Italy
来源：
NEUROSCIENCE LETTERS | 2003年 / 336卷 / 02期
关键词：
parietal cortex; hemineglect; low-frequency repetitive transcranial magnetic stimulation; cortical inhibition; rehabilitation;
D O I：
10.1016/S0304-3940(02)01283-1
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The aim of the study was to investigate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected hemisphere can ameliorate visuospatial neglect. We treated three right brain damaged patients with left neglect. 900 pulses (1 Hz frequency) were given over left posterior parietal cortex every other day for 2 weeks. Patients performed a computerized task requiring length judgement of prebisected lines, tachistoscopically presented for 150 ms. With respect to rTMS the task was given 15 days before, at the beginning, at the end and 15 days after. At these times patients performed also line bisection and clock drawing tasks. rTMS induced a significant improvement of visuo-spatial performance that remained quite unchanged 15 days after. Patients performance at Time 3 and 4 improved also as concerns line bisection and clock drawing tasks. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
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收藏
页码：131 / 133
页数：3
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