Combinatorial synthesis of carbohydrate cluster on tree-type linker with orthogonally cleavable parts

被引：4

作者：

Amaya, T ^{[1
]}

Tanaka, H ^{[1
]}

Takahashi, T ^{[1
]}

机构：

[1] Tokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Tokyo 1528552, Japan

来源：

SYNLETT | 2004年 / 03期

关键词：

combinatorial synthesis; solid-phase synthesis; orthogonal cleavage; carbohydrate cluster; library; tree-type linker;

D O I：

10.1055/s-2004-815421

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have successfully developed a synthetic strategy or the combinatorial solid-phase synthesis of carbohydrate clusters on a tree-type linker with two types of orthogonally cleavable parts. The combination of three types of spacers, two types of carbohydrate ligands, and two types of orthogonal cleavage provided a 12-member carbohydrate cluster library (6 dimers and 6 tetramers).

引用

页码：497 / 502

页数：6

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