Cluster of cases of acute hepatitis associated with hepatitis E virus infection acquired in the Netherlands

被引：76

作者：

Widdowson, MA

Jaspers, WJM

van der Poel, WHM

Verschoor, F

Husman, AMD

Winter, HLJ

Zaaijer, HL

Koopmans, M

机构：

[1] European Programme Intervent Epidemiol & Training, Bilthoven, Netherlands

[2] Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands

[3] St Lucas Hosp, Winschoten, Netherlands

[4] Reg Publ Hlth Lab Groningen & Drenthe, Groningen, Netherlands

[5] Blood Transfus Serv, Sanquin Cent Lab, Amsterdam, Netherlands

来源：

CLINICAL INFECTIOUS DISEASES | 2003年 / 36卷 / 01期

关键词：

D O I：

10.1086/345439

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Increasing evidence suggests that hepatitis E virus (HEV) infection may occur in developed countries and that swine may act as a reservoir. We report a cluster of 2 confirmed cases and 1 presumptive case of hepatitis associated with HEV. The typed strain from 1 case was related to HEV strains found in North America and Europe, and it was also related to a cluster of swine HEV strains found in The Netherlands. Our findings indicate that locally acquired HEV infections in industrialized countries may be overlooked. Routine testing for HEV infection in patients with acute hepatitis in The Netherlands should be considered before a diagnosis of autoimmune hepatitis is reached and steroid therapy is initiated.

引用

页码：29 / 33

页数：5

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