Leucovorin modulation of fluorouracil in advanced colorectal cancer

被引：10

作者：

deGramont, A

Louvet, C

Andre, T

Tournigand, C

Raymond, E

Molitor, JL

Krulik, M

机构：

来源：

REVUE DE MEDECINE INTERNE | 1997年 / 18卷

关键词：

leucovorin; 5FU; metastatic colorectal cancer;

D O I：

10.1016/S0248-8663(97)83768-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Leucovorin modulation of fluorouracil in advanced colorectal cancer. The rational of leucovorin modulation of 5-fluorouracil nad the clinical results in colorectal cancer are reviewed with special emphasis on the monthly schedule of low dose leucovorin and 5FU bolus for 5 consecutive days (NCCTG-Mayo Clinic regimen) and the bimonthly schedule of high-dose leucovorin and 5FU bolus plus continous infusion for two consecutive days (LV5FU2) which is now considered as a new standard.

引用

页码：S372 / S378

页数：7

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