Antithrombin activity of some constituents from Origanum vulgare

被引：37

作者：

Goun, E

Cunningham, G

Solodnikov, S

Krasnykch, O

Miles, H ^{[1
]}

机构：

[1] Univ Cent Florida, Dept Chem, Orlando, FL 32816 USA

[2] Perm State Univ, Dept Biol, Perm 614000, Russia

来源：

FITOTERAPIA | 2002年 / 73卷 / 7-8期

关键词：

Origanum vulgare; aristolochic acid I and II; D-(+)-raffinose; antithrombin activity; anticancer activity;

D O I：

10.1016/S0367-326X(02)00245-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Aristolochic acid I, aristolochic acid II and D-(+)-raffinose were isolated from Origanum vulgare. Their inhibition of thrombin and activity against leukemia were evaluated. Aristolochic acid I and II have high inhibition of thrombin activity and were confirmed to possess activity against cancer. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：692 / 694

页数：3

共 13 条

[1]

ANGELES LT, 1970, J PHILIPP MED ASSOC, V46, P505

[2]

ANGELES LT, 1963, FARMACO, V24, P1259

[3]

Antimicrobial agents from plants: antibacterial activity of plant volatile oils [J].