In vitro Biocompatibility of New Silver(I) Coordination Compound Coated-Surfaces for Dental Implant Applications

被引:31
作者
Brunetto, Priscilla S. [1 ]
Slenters, Tuende Vig [1 ]
Fromm, Katharina M. [1 ]
机构
[1] Univ Fribourg, Dept Chem, CH-1700 Fribourg, Switzerland
关键词
silver; cytotoxicity; biocompatibility; STRUCTURE-PROPERTY RELATIONSHIPS; ETHANEDIYL BIS(ISONICOTINATE); PROTEIN ADSORPTION; POLYMER SURFACES; CELL ATTACHMENT; BEHAVIOR; ANTIBACTERIAL; FIBRONECTIN; ADHESION; DEVICES;
D O I
10.3390/ma4020355
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070305 [高分子化学与物理];
摘要
Biofilm formation on implant materials causes a common problem: resistance to aggressive pharmacological agents as well as host defenses. Therefore, to reduce bacterial adhesion to implant surfaces we propose to use silver(I) coordination networks as it is known that silver is the most powerful antimicrobial inorganic agent. As a model surface, self-assembled monolayers (SAMs) on gold Au(111) was used to permit permanent attachment of our silver(I) coordination networks. The surface coatings showed typical nano-structured surfaces with a good biocompatibility for soft-tissue integration with fibroblast cells.
引用
收藏
页码:355 / 367
页数:13
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