Stem cells from umbilical cord blood

被引：23

作者：

Sanchez-Ramos, Juan ^{[1
]}

机构：

[1] Univ S Florida, Dept Neurol MDC 55, Tampa, FL 33612 USA

来源：

SEMINARS IN REPRODUCTIVE MEDICINE | 2006年 / 24卷 / 05期

关键词：

stem cells; umbilical cord blood; plasticity; central nervous system;

D O I：

10.1055/s-2006-952150

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The study of hematopolesis, the generation of blood cell lines throughout life, has provided conceptual, experimental, and therapeutic approaches useful to an stem cell biologists. From a clinical perspective, no other area of stem cell biology has been applied as successfully as has transplantation of bone marrow and cord blood for the treatment of blood diseases. In the last few years, research in stem cell biology has expanded rapidly to include the study of stem cells from embryonic, fetal, and various adult tissues, engendering novel perspectives regarding the identity, origin, and full therapeutic potential of tissue-specific item cells. Rather than focusing on the use of cord blood stem cells for reconstitution of bone marrow, this article reviews the biology of stem cells found in the cord blood in the context of cell plasticity and their therapeutic potential for repair of the nervous system.

引用

页码：358 / 369

页数：12

共 81 条

[41] Transdifferentiation - Fact or artifact [J].

Liu, Y ;

Rao, MS .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2003, 88 (01) :29-40

[42] Stem cells from bone marrow, umbilical cord blood and peripheral blood for clinical application: Current status and future application [J].

Lu, L ;

Shen, RN ;

Broxmeyer, HE .

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 1996, 22 (02) :61-78

[43] Cardiomyocytes can be generated from marrow stromal cells in vitro [J].

Makino, S ;

Fukuda, K ;

Miyoshi, S ;

Konishi, F ;

Kodama, H ;

Pan, J ;

Sano, M ;

Takahashi, T ;

Hori, S ;

Abe, H ;

Hata, J ;

Umezawa, A ;

Ogawa, S .

JOURNAL OF CLINICAL INVESTIGATION, 1999, 103 (05) :697-705

[44] EMBRYONIC EXPRESSION OF A HEMATOPOIETIC GROWTH-FACTOR ENCODED BY THE SI LOCUS AND THE LIGAND FOR C-KIT [J].

MATSUI, Y ;

ZSEBO, KM ;

HOGAN, BLM .

NATURE, 1990, 347 (6294) :667-669

[45] Umbilical cord blood stem cells can expand hematopoietic and neuroglial progenitors in vitro [J].

McGuckin, CP ;

Forraz, N ;

Allouard, Q ;

Pettengell, R .

EXPERIMENTAL CELL RESEARCH, 2004, 295 (02) :350-359

[46] Stem cells in the central nervous system [J].

McKay, R .

SCIENCE, 1997, 276 (5309) :66-71

[47] Turning blood into brain:: Cells bearing neuronal antigens generated in vivo from bone marrow [J].

Mezey, É ;

Chandross, KJ ;

Harta, G ;

Maki, RA ;

McKercher, SR .

SCIENCE, 2000, 290 (5497) :1779-1782

[48] Infusion of human umbilical cord blood ameliorates neurologic deficits in rats with hemorrhagic brain injury [J].

Nan, ZH ;

Grande, A ;

Sanberg, CD ;

Sanberg, PR ;

Low, WC .

STEM CELL BIOLOGY: DEVELOPMENT AND PLASTICITY, 2005, 1049 :84-96

[49] BONE-MARROW TRANSPLANT IN A CASE OF MUCOPOLYSACCHARIDOSIS-I SCHEIE PHENOTYPE - SKIN ULTRASTRUCTURE BEFORE AND AFTER TRANSPLANTATION [J].

NAVARRO, C ;

DOMINGUEZ, C ;

COSTA, M ;

ORTEGA, JJ .

ACTA NEUROPATHOLOGICA, 1991, 82 (01) :33-38

[50] Microchimerism: incidental byproduct of pregnancy or active participant in human health? [J].

Nelson, JL .

TRENDS IN MOLECULAR MEDICINE, 2002, 8 (03) :109-113

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