Controlling charge states of large ions

被引：151

作者：

Scalf, M ^{[1
]}

Westphall, MS ^{[1
]}

Krause, J ^{[1
]}

Kaufman, SL ^{[1
]}

Smith, LM ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

SCIENCE | 1999年 / 283卷 / 5399期

关键词：

D O I：

10.1126/science.283.5399.194

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The charge state of ions produced in electrospray ionization (ESI) was reduced in a controlled manner to yield predominantly singly charged species by exposure of the aerosol to a bipolar ionizing gas. Analysis of the resulting ions on an orthogonal time-of-flight mass spectrometer yielded mass spectra greatly simplified compared with conventional ESI spectra, The decreased spectral complexity afforded by the charge reduction facilitates the analysis of mixtures by ESI mass spectrometry.

引用

页码：194 / 197

页数：4

共 45 条

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