Bacterial meningitis in children: A French prospective study

被引：67

作者：

Bingen, E

Levy, C

de La Rocque, F

Boucherat, M

Varon, E

Alonso, JM

Dabernat, H

Reinert, P

Aujard, Y

Cohen, R

机构：

[1] Hop Robert Debre, Microbiol Serv, EA3105, F-75019 Paris, France

[2] French Pediat Soc, Pediat Infect Dis Grp, Bordeaux, France

[3] Assoc Clin & Therapeut Infantile Val De Marne, St Maur, France

[4] Hop Georges Pompidou, Natl Reference Ctr Streptococcus Pneumol, Paris, France

[5] Inst Pasteur, Natl Reference Ctr Neisseria Meningitidis, Paris, France

[6] Hop Robert Debre, Serv Neonatol, F-75019 Paris, France

[7] Hop Purpan, Natl Reference Ctr Haemophilus Influenzae, Toulouse, France

[8] Ctr Hosp Intercommunal Creteil, Microbiol Serv, Creteil, France

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 41卷 / 07期

关键词：

D O I：

10.1086/432944

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

From January 2001 through December 2003, a total of 1084 children with bacterial meningitis were enrolled in a prospective French nationwide survey. The most frequent pathogens found in children older than 28 days were Neisseria meningitis (55.3%) and Streptococcus pneumoniae (33.4%). S. pneumoniae was the most frequent pathogen found among infants aged 2-12 months (49.5%), whereas N. meningitidis was the most frequent pathogen among children 112 months old (69.7%). Approximately one-half of S. pneumoniae isolates had diminished susceptibility to penicillin. The case-fatality rates were 7.6% for children with N. meningitidis meningitis and 10.8% for children with S. pneumoniae infection.

引用

页码：1059 / 1063

页数：5

共 12 条

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