Taming the isobaric tagging elephant in the room in quantitative proteomics

被引:18
作者
Christoforou, Andy [1 ]
Lilley, Kathryn S. [1 ]
机构
[1] Univ Cambridge, Dept Biochem, Cambridge Ctr Prote, Cambridge Syst Biol Ctr, Cambridge CB2 1QW, England
关键词
QUANTIFICATION;
D O I
10.1038/nmeth.1736
中图分类号
Q5 [生物化学];
学科分类号
070307 [化学生物学];
摘要
[No abstract available]
引用
收藏
页码:911 / +
页数:2
相关论文
共 11 条
[1]
Addressing Accuracy and Precision Issues in iTRAQ Quantitation [J].
Karp, Natasha A. ;
Huber, Wolfgang ;
Sadowski, Pawel G. ;
Charles, Philip D. ;
Hester, Svenja V. ;
Lilley, Kathryn S. .
MOLECULAR & CELLULAR PROTEOMICS, 2010, 9 (09) :1885-1897
[2]
High Precision Quantitative Proteomics Using iTRAQ on an LTQ Orbitrap: A New Mass Spectrometric Method Combining the Benefits of All [J].
Koecher, Thomas ;
Pichler, Peter ;
Schutzbier, Michael ;
Stingl, Christoph ;
Kaul, Axel ;
Teucher, Nils ;
Hasenfuss, Gerd ;
Penninger, Josef M. ;
Mechtler, Karl .
JOURNAL OF PROTEOME RESEARCH, 2009, 8 (10) :4743-4752
[3]
iTRAQ Underestimation in Simple and Complex Mixtures: "The Good, the Bad and the Ugly" [J].
Ow, Saw Yen ;
Salim, Malinda ;
Noirel, Josselin ;
Evans, Caroline ;
Rehman, Ishtiaq ;
Wright, Phillip C. .
JOURNAL OF PROTEOME RESEARCH, 2009, 8 (11) :5347-5355
[4]
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents [J].
Ross, PL ;
Huang, YLN ;
Marchese, JN ;
Williamson, B ;
Parker, K ;
Hattan, S ;
Khainovski, N ;
Pillai, S ;
Dey, S ;
Daniels, S ;
Purkayastha, S ;
Juhasz, P ;
Martin, S ;
Bartlet-Jones, M ;
He, F ;
Jacobson, A ;
Pappin, DJ .
MOLECULAR & CELLULAR PROTEOMICS, 2004, 3 (12) :1154-1169
[5]
Targeted Data Acquisition for Improved Reproducibility and Robustness of Proteomic Mass Spectrometry Assays [J].
Savitski, Mikhail M. ;
Fischer, Frank ;
Mathieson, Toby ;
Sweetman, Gavain ;
Lang, Manja ;
Bantscheff, Marcus .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2010, 21 (10) :1668-1679
[6]
A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods [J].
Shirran, Sally L. ;
Botting, Catherine H. .
JOURNAL OF PROTEOMICS, 2010, 73 (07) :1391-1403
[7]
Undesirable Charge-Enhancement of Isobaric Tagged Phosphopeptides Leads to Reduced Identification Efficiency [J].
Thingholm, Tine E. ;
Palmisano, Giuseppe ;
Kjeldsen, Frank ;
Larsen, Martin R. .
JOURNAL OF PROTEOME RESEARCH, 2010, 9 (08) :4045-4052
[8]
Tandem mass tags:: A novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS [J].
Thompson, A ;
Schäfer, J ;
Kuhn, K ;
Kienle, S ;
Schwarz, J ;
Schmidt, G ;
Neumann, T ;
Hamon, C .
ANALYTICAL CHEMISTRY, 2003, 75 (08) :1895-1904
[9]
Ting L, 2011, NAT METHODS, V8, P937, DOI [10.1038/NMETH.1714, 10.1038/nmeth.1714]
[10]
Wenger CD, 2011, NAT METHODS, V8, P933, DOI [10.1038/NMETH.1716, 10.1038/nmeth.1716]