共 5 条
A novel approach to surface plasmon resonance multichannel sensing
被引:11
作者:
Homola, J
[1
]
Dostálek, J
[1
]
Ctyroky, J
[1
]
机构:
[1] Inst Radio Engn & Elect, CZ-18251 Prague 8, Czech Republic
来源:
OPTICAL ENGINEERING FOR SENSING AND NANOTECHNOLOGY (ICOSN 2001)
|
2001年
/
4416卷
关键词:
surface plasmon resonance;
optical sensors;
biosensors;
D O I:
10.1117/12.427017
中图分类号:
O43 [光学];
学科分类号:
070207 ;
0803 ;
摘要:
We present a novel surface plasmon resonance (SPR) sensor based on serial organization of sensing channels and sequential spectral encoding of responses from sensing channels into an optical spectrum. This approach allows probing interfacial processes by surface plasmons of different field profiles which makes it possible to distinguish surface and bulk contributions to SPR sensor response. We illustrate this unique feature of the presented approach in a model biosensing experiment in which the detection of human chorigonadotropin (hCG) is compensated for background refractive index interference.
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页码:86 / 89
页数:4
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