Food allergy in children

被引:24
作者
Baral, VR [1 ]
Hourihane, JO [1 ]
机构
[1] Univ Southampton, Infect Inflammat & Repair Div, Southampton SO9 5NH, Hants, England
关键词
D O I
10.1136/pgmj.2004.030288
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Food allergy is being increasingly recognised with the highest prevalence being in preschool children. Pathogenesis varies so diagnosis rests on careful history and clinical examination, appropriate use of skin prick and serum-specific IgE testing, food challenge, and supervised elimination diets. A double blind placebo controlled food challenge is the gold standard diagnostic test. Avoidance of the allergenic food is the key towards successful management. IgE mediated food allergy may present as a potentially fatal anaphylactic reaction, and management consists of the appropriate use of adrenaline (epinephrine) and supportive measures. Sensitisation remains a key target for intervention. Disease modifying agents are currently under trial for managing difficult allergies. Management requires a multidisciplinary approach and follow up.
引用
收藏
页码:693 / 701
页数:9
相关论文
共 62 条
[1]   MEASLES IMMUNIZATION IN CHILDREN WITH ALLERGY TO EGG [J].
AICKIN, R ;
HILL, D ;
KEMP, A .
BRITISH MEDICAL JOURNAL, 1994, 309 (6949) :223-225
[2]  
Alves B, 2001, ARCH DIS CHILD, V85, P349
[3]  
[Anonymous], CURRENT PAEDIAT
[4]   Science commentary: Th1 and Th2 responses: what are they? [J].
Berger, A .
BRITISH MEDICAL JOURNAL, 2000, 321 (7258) :424-424
[5]  
Bernardini R, 1995, Ann Ist Super Sanita, V31, P481
[6]   Standardization of food challenges in patients with immediate reactions to foods - position paper from the European Academy of Allergology and Clinical Immunology [J].
Bindslev-Jensen, C ;
Ballmer-Weber, BK ;
Bengtsson, U ;
Blanco, C ;
Ebner, C ;
Hourihane, J ;
Knulst, AC ;
Moneret-Vautrin, DA ;
Nekam, K ;
Niggemann, B ;
Osterballe, M ;
Ortolani, C ;
Ring, J ;
Schnopp, C ;
Werfel, T .
ALLERGY, 2004, 59 (07) :690-697
[7]   Fatalities due to anaphylactic reactions to foods [J].
Bock, SA ;
Muñoz-Furlong, A ;
Sampson, HA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 107 (01) :191-193
[8]   Improving diagnostic tests for food allergy with recombinant allergens [J].
Bohle, B ;
Vieths, S .
METHODS, 2004, 32 (03) :292-299
[9]   Efficacy of birch-pollen immunotherapy on cross-reactive food allergy confirmed by skin tests and double-blind food challenges [J].
Bolhaar, STHP ;
Tiemessen, MM ;
Zuidmeer, L ;
van Leeuwen, A ;
Hoffmann-Sommergruber, K ;
Bruijnzeel-Koomen, CAFM ;
Taams, LS ;
Knol, EF ;
van Hoffen, E ;
van Ree, R ;
Knulst, AC .
CLINICAL AND EXPERIMENTAL ALLERGY, 2004, 34 (05) :761-769
[10]  
*BRIT MED ASS ROYA, 2004, BRIT NAT FORM