A consensus Porphyromonas gingivalis promoter sequence

被引：18

作者：

Jackson, CA ^{[1
]}

Hoffmann, B ^{[1
]}

Slakeski, N ^{[1
]}

Cleal, S ^{[1
]}

Hendtlass, AJ ^{[1
]}

Reynolds, EC ^{[1
]}

机构：

[1] Univ Melbourne, Sch Dent Sci, Biochem & Mol Biol Unit, Melbourne, Vic 3000, Australia

来源：

FEMS MICROBIOLOGY LETTERS | 2000年 / 186卷 / 01期

关键词：

RNA polymerase; sigma-70; transcription start point; promoter; expression; Porphyromonas gingivalis;

D O I：

10.1111/j.1574-6968.2000.tb09094.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have determined the transcription start points (tsp) for recently identified Porphyromonas gingivalis W50 genes, kgp, rgpA, rgpB (formerly designated prtK, prtR, and prtRII respectively), fetB and the mcmAB operon. Alignment of the DNA upstream of these rsp and those from the literature has enabled us to identify consensus sequences that may represent a P. gingivalis promoter. There is a potential -10 hexamer sequence, 5'-TATATT-3' centred on average at -10/11 nt which is repeated at -19/20 nt and an upstream consensus, 5'-CAGAT(A/G)-3' which is centred at -39/40 nt. (C) 2000 Published by Elsevier Science B.V. All rights reserved.

引用

页码：133 / 138

页数：6

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