Myoglobin as a case study for molecular simulations in the presence of a microwave electromagnetic field

被引：8

作者：

Apollonio, Francesca ^{[1
]}

D'Abramo, Marco ^{[2
]}

Liberti, Micaela ^{[1
]}

Amadei, Andrea ^{[2
]}

Di Nola, Alfredo ^{[1
]}

D'Inzeo, Guglielmo ^{[1
]}

机构：

[1] Univ Roma La Sapienza, ICEmB, Rome, Italy

[2] Univ Rome, Dept Chem, Rome, Italy

来源：

2006 IEEE MTT-S INTERNATIONAL MICROWAVE SYMPOSIUM DIGEST, VOLS 1-5 | 2006年

关键词：

microwave; molecular simulations; myoglobin;

D O I：

10.1109/MWSYM.2006.249719

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Molecular simulations of biochemical processes seem to be a promising tool to understand the mechanisms through which an EM field can interact with a biological system. Here the action of a MW signal on the binding process of a ligand to a protein active site has been studied choosing myoglobin as a reference molecular model. The methodology used permits to follow the dynamic evolution of the chemical reaction in the system with an extremely rigorous approach based on quantum analysis.

引用

页码：1746 / +

页数：2

共 8 条

[1]

Apollonio F, 2000, IEEE T MICROW THEORY, V48, P2082, DOI 10.1109/22.884199

[2] Conformational fluctuations and electronic properties in Myoglobin [J].