A short and efficient enantioselective synthesis of cyclohexylnorstatine, a key component of a renin inhibitor

被引：23

作者：

Upadhya, TT ^{[1
]}

Sudalai, A ^{[1
]}

机构：

[1] NATL CHEM LAB,DIV ORGAN CHEM,PUNE 411008,MAHARASHTRA,INDIA

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 21期

关键词：

D O I：

10.1016/S0957-4166(97)00500-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A catalytic asymmetric synthesis of ethyl (2R, 3S)-N-(p-toluenesulfonyl)-3-amino-4-cyclohexyl-2-hydroxybutyrate 7 in 96% ee from cheaply available cyclohexanone is described employing Sharpless asymmetric aminohydroxylation as the key step. (C) 1997 Elsevier Science Ltd.

引用

页码：3685 / 3689

页数：5

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