Microbial genetics - The tinkerer's evolving tool-box

被引:69
作者
Moxon, ER
Thaler, DS
机构
[1] JOHN RADCLIFFE HOSP,INST MOL MED,OXFORD OX3 9DU,ENGLAND
[2] ROCKEFELLER UNIV,SACKLER LAB MOL GENET & INFORMAT,NEW YORK,NY 10021
关键词
D O I
10.1038/42607
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
By knowing the mechanisms through which genetic variants are generated, we should gain a better understanding of evolution. Two new papers — one theoretical and one experimental — show that mutator alleles (which can lead to a huge increase in mutation rate) can speed up the rate at which bacteria adapt to a changing environment, even if these alleles remain at a low frequency.
引用
收藏
页码:659 / &
页数:3
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