Downscaling aspects of a conductivity detector for application in on-chip capillary electrophoresis

被引：45

作者：

Laugere, F ^{[1
]}

Lubking, GW ^{[1
]}

Berthold, A ^{[1
]}

Bastemeijer, J ^{[1
]}

Vellekoop, MJ ^{[1
]}

机构：

[1] Delft Univ Technol, DIMES, Elect Instrumentat Lab, NL-2628 CD Delft, Netherlands

来源：

SENSORS AND ACTUATORS A-PHYSICAL | 2001年 / 92卷 / 1-3期

关键词：

conductivity detector; miniaturization; capacitively coupled; 4-electrode probe; silicon carbide;

D O I：

10.1016/S0924-4247(01)00547-7

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We are presenting the experimental results of capacitively coupled 2- and 4-electrode conductivity detector fabricated as a glass dip-stick. These results are used as a starting point for investigating the consequences of downscaling the device for on-chip capillary electrophoresis (CE) applications, where the detector is located in a separation microchannel. Our studies show that, it is possible to do accurate and sensitive conductivity sensing in a 150 mum wide channel, by making use of 4-electrode set-up with silicon carbide (SiC) thin insulating layers on top of the electrodes. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：109 / 114

页数：6

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