Cytokine elevations in acute coronary syndrome and ovarian cancer: A mechanism for the up-regulation of the acute phase proteins in these different disease etiologies

被引：19

作者：

Kavsak, Peter A. ^{[1
]}

Lee, Agnes ^{[2
]}

Hirte, Hal ^{[3
]}

Young, Ed ^{[1
]}

Gauldie, Jack ^{[1
,4
]}

机构：

[1] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada

[2] McMaster Univ, Dept Med, Hamilton, ON, Canada

[3] McMaster Univ, Dept Oncol, Hamilton, ON, Canada

[4] McMaster Univ, Ctr Gene Therapeut, Hamilton, ON, Canada

来源：

CLINICAL BIOCHEMISTRY | 2008年 / 41卷 / 7-8期

关键词：

cytokines; myocardial infarction; ovarian cancer; profile;

D O I：

10.1016/j.clinbiochem.2008.01.019

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Objectives: To identify if a common set of cytokines is elevated in both ovarian cancer and acute coronary syndrome (ACS). Design and methods: A cytokine array (Randox Ltd) was measured in healthy women (n=33), women with ACS (n=21) and ovarian cancer (17-45). Results: Women with ACS or ovarian cancer had higher concentrations of IL-6, IL-8, VEGF, MCP-1, and EGF as compared to healthy volunteers. Discussion: Common cytokine elevations are present in both ACS and ovarian cancer. (C) 2008 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

引用

页码：607 / 610

页数：4