Endothelial nitric oxide synthase (eNOS) is localized to Muller cells in all vertebrate retinas

被引：53

作者：

Haverkamp, S

Kolb, H ^{[1
]}

Cuenca, N

机构：

[1] Univ Utah, John Moran Eye Ctr, Salt Lake City, UT 84032 USA

[2] Univ Oldenburg, Dept Neurobiol, D-2900 Oldenburg, Germany

[3] Univ Alicante, Dept Biotechnol, E-03080 Alicante, Spain

来源：

VISION RESEARCH | 1999年 / 39卷 / 14期

关键词：

immunostaining; glial cells; astrocytes; horizontal cell axon terminals;

D O I：

10.1016/S0042-6989(99)00007-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The distribution of endothelial nitric oxide synthase immunoreactivity (eNOS-IR) was investigated in the retinas of all phylogenetic vertebrate classes by using a monoclonal eNOS antibody. Confocal light microscopy showed immunoreactive labeling in Muller cells of fish, frog, salamander, turtle, chicken, rat, ground squirrel, and monkey retina. In vascularized retinas (rat, monkey), astrocytes and some blood vessels were also stained. Furthermore, eNOS-IR was localized to axon terminals of turtle and fish horizontal cells. These observations are the first to show the presence of eNOS-IR in Muller glia and horizontal cell structures of the vertebrate retina. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2299 / 2303

页数：5

共 37 条

[31] Connexin50, a gap junction protein of macroglia in the mammalian retina and visual pathway [J].