The Yin-Yang of Tumor-Associated Neutrophils

被引:125
作者
Mantovani, Alberto [1 ,2 ]
机构
[1] Univ Milan, Ist Clin Humantas IRCCS, I-20089 Milan, Italy
[2] Univ Milan, Dept Translat Med, I-20089 Milan, Italy
关键词
MAMMARY CARCINOMAS; MACROPHAGES; CELLS; METASTASIS;
D O I
10.1016/j.ccr.2009.08.014
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cancer-related inflammation is a key component of the tumor microenvironment. A report in this issue of Cancer Cell now indicates that tumor-associated neutrophils in lung cancer can polarize to either "N1" or "N2" phenotype that inhibits or promotes cancer development, respectively.
引用
收藏
页码:173 / 174
页数:2
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